Trait
SNPs associated with Cleft palate, cleft lip
64 genetic variants across 18 genes have been associated with Cleft palate, cleft lip in published research. Key genes include ABCA4, BACH2, CYRIA.
Associated variants64 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs17242358 | — | GWAS association (p=4.0e-24) | Large GWAS |
| rs7552 | CYRIA | GWAS association (p=6.0e-22) | Large GWAS |
| rs2235371 | IRF6 | GWAS association (p=9.0e-22) | Large GWAS |
| rs4791774 | NTN1 | GWAS association (p=5.0e-19) | Large GWAS |
| rs2064163 | — | GWAS association (p=9.0e-19) | Large GWAS |
| rs7017252 | — | GWAS association (p=8.0e-16) | Large GWAS |
| rs7839784 | — | GWAS association (p=2.0e-14) | Large GWAS |
| rs11066150 | NAA25 | GWAS association (p=3.0e-13) | Large GWAS |
| rs9439714 | — | GWAS association (p=3.0e-13) | Large GWAS |
| rs1854110 | — | GWAS association (p=4.0e-13) | Large GWAS |
| rs6585429 | VAX1 | GWAS association (p=7.0e-13) | Large GWAS |
| rs2304269 | — | GWAS association (p=1.0e-12) | Large GWAS |
| rs957448 | VIRMA | GWAS association (p=1.0e-12) | Large GWAS |
| rs481931 | ABCA4 | GWAS association (p=1.0e-12) | Large GWAS |
| rs72741048 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs3741442 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs8049367 | — | GWAS association (p=9.0e-12) | Large GWAS |
| rs2872615 | — | GWAS association (p=9.0e-12) | Large GWAS |
| rs6129653 | — | GWAS association (p=9.0e-12) | Large GWAS |
| rs12543318 | — | GWAS association (p=9.0e-12) | Large GWAS |
| rs1838105 | GOSR2 | GWAS association (p=1.0e-11) | Large GWAS |
| rs13041247 | LOC102724968 | GWAS association (p=2.0e-11) | Large GWAS |
| rs2289187 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs6495117 | — | GWAS association (p=6.0e-11) | Large GWAS |
| rs12944377 | — | GWAS association (p=6.0e-11) | Large GWAS |
| rs2283487 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs12681366 | RAD54B | GWAS association (p=2.0e-10) | Large GWAS |
| rs12229892 | PTPN11 | GWAS association (p=2.0e-10) | Large GWAS |
| rs7078160 | SHTN1 | GWAS association (p=3.0e-10) | Large GWAS |
| rs1243572 | — | GWAS association (p=4.0e-10) | Large GWAS |
| rs10512248 | PTCH1 | GWAS association (p=5.0e-10) | Large GWAS |
| rs55768865 | — | GWAS association (p=6.0e-10) | Large GWAS |
| rs4901118 | — | GWAS association (p=7.0e-10) | Large GWAS |
| rs705704 | RPS26 | GWAS association (p=1.0e-09) | Large GWAS |
| rs9545308 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs2600519 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs13385292 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs4952552 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs9381107 | — | GWAS association (p=3.0e-09) | Large GWAS |
| rs926348 | IRF6 | GWAS association (p=4.0e-09) | Large GWAS |
| rs78212183 | DEPDC5 | GWAS association (p=5.0e-09) | Large GWAS |
| rs287982 | — | GWAS association (p=6.0e-09) | Large GWAS |
| rs7871395 | — | GWAS association (p=6.0e-09) | Large GWAS |
| rs227731 | — | GWAS association (p=9.0e-09) | Large GWAS |
| rs12229654 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs10462065 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs6465810 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs4112328 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs2802532 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs3746101 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs7148069 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs1907989 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs628271 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs11583072 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs2006771 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs181737795 | BACH2 | GWAS association (p=3.0e-08) | Large GWAS |
| rs10483604 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs1347188 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs13317 | FGFR1 | GWAS association (p=4.0e-08) | Large GWAS |
| rs908822 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs2221169 | — | GWAS association (p=5.0e-08) | Large GWAS |
| rs187523265 | PHLDB1 | GWAS association (p=5.0e-08) | Large GWAS |
| rs6740960 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs72728755 | — | GWAS association (p=3.0e-32) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.