rs4112328
This is a intergenic variant variant.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Orofacial cleft
Dack K et al. “Genetic heterogeneity and homogeneity among orofacial cleft subtypes: genome-wide association studies in the cleft collective.” Human Molecular Genetics 34(23):1934-1950 (2025)
Allele A
OR 1.22
p 4.0e-9
N 10,181
Large GWAS
European
Cleft palate, cleft lip
Dack K et al. “Genetic heterogeneity and homogeneity among orofacial cleft subtypes: genome-wide association studies in the cleft collective.” Human Molecular Genetics 34(23):1934-1950 (2025)
Allele A
OR 1.34
p 1.0e-8
N 8,750
Large GWAS
European
cleft lip
Dack K et al. “Genetic heterogeneity and homogeneity among orofacial cleft subtypes: genome-wide association studies in the cleft collective.” Human Molecular Genetics 34(23):1934-1950 (2025)
Allele A
OR 1.26
p 2.0e-8
N 9,280
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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