NTN1

netrin 1

Summary

Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of netrin suggest that variation in netrin may be involved in cancer development. [provided by RefSeq, Jul 2008]

Known Variants81 total

rsidPosition (GRCh37)AllelesClassClinVar
rs250850767517:8,925,736G/T—likely benign
rs76403107517:8,925,806A/G—uncertain significance
rs75360164717:8,925,807T/C—likely benign
rs37633247817:8,925,810C/T—likely benign
rs36964732617:8,925,909C/T—likely benign
rs105164347217:8,925,910C/T—uncertain significance
rs37538078217:8,925,964C/A—uncertain significance
rs7326215217:8,926,032G/T—benign
rs100899973417:8,926,051C/A—uncertain significance
rs20018792417:8,926,061A/C—uncertain significance
rs57133414217:8,926,074C/G—uncertain significance
rs145196646317:8,926,176C/G—uncertain significance
rs14602099917:8,926,209C/T—likely benign
rs75779232517:8,926,210T/C—uncertain significance
rs209185741817:8,926,226C/T—uncertain significance
rs75141036417:8,926,247A/G—uncertain significance
rs20173691117:8,926,301C/G—uncertain significance
rs19967430117:8,926,318A/G—likely benign
rs3407925617:8,926,321C/A—likely benign
rs209185809617:8,926,325C/T—uncertain significance
rs209185846717:8,926,415T/C—uncertain significance
rs86850372917:8,926,420G/A—uncertain significance
rs14453572617:8,926,422C/G—likely benign
rs76207666117:8,926,435G/T—uncertain significance
rs250851041017:8,926,444A/T—uncertain significance
rs74582081217:8,926,461C/T—likely benign
rs76693506817:8,926,467C/G—uncertain significance
rs119520491917:8,926,553A/G—uncertain significance
rs130088057717:8,926,568G/A—uncertain significance
rs74578463117:8,926,604A/T—uncertain significance
rs250851101117:8,926,611G/A—likely benign
rs11301688017:8,926,623C/T—benign
rs188064617:8,929,845A/T——
rs740622617:8,930,225A/Gintron variant—
rs479133117:8,932,082C/Tintron variantuncertain significance
rs479177417:8,932,119A/C——
rs722366817:8,933,194A/Gintron variant—
rs720851517:8,933,343T/Aintron variant—
rs989144617:8,935,416C/T——
rs807645717:8,943,929T/A——
rs1695782117:8,948,104C/A——
rs7280998617:8,984,022G/Aintron variant—
rs989720017:8,985,510G/Tintron variant—
rs1294245917:9,010,794T/Cintron variant—
rs20118979917:9,066,123C/A—likely benign
rs250789007417:9,066,150G/T—uncertain significance
rs5568715317:9,066,248T/C—benign
rs228651117:9,066,254T/C—benign
rs74758391517:9,066,279G/A—uncertain significance
rs378597717:9,080,571G/Acoding sequence variant—
rs14038092117:9,083,200C/T—benign
rs250791804217:9,083,214C/T—uncertain significance
rs77940819217:9,083,228G/A—uncertain significance
rs250791822517:9,083,268G/A—uncertain significance
rs990683417:9,083,631G/T——
rs990881017:9,083,753C/T——
rs989005017:9,084,868A/Gupstream gene variant—
rs37032015817:9,086,251C/T—uncertain significance
rs36854096817:9,086,252G/A—likely benign
rs77772569517:9,086,257C/T—uncertain significance
rs77068539117:9,086,271G/A—uncertain significance
rs6206819917:9,086,708T/Cupstream gene variant—
rs378598217:9,090,224C/Tintron variant—
rs20020981617:9,124,480T/A—uncertain significance
rs37607153517:9,124,489C/T—likely benign
rs76135965217:9,124,490G/A—uncertain significance
rs119963326117:9,142,959G/A—uncertain significance
rs74893184117:9,142,990C/T—uncertain significance
rs76645355617:9,143,029T/C—uncertain significance
rs250809055817:9,143,043A/G—uncertain significance
rs75691043317:9,143,061G/C—uncertain significance
rs250809090617:9,143,071G/A—uncertain significance
rs190612127917:9,143,081C/T—likely benign
rs126989699217:9,143,120G/A—likely benign
rs77452328117:9,143,152C/T—uncertain significance
rs117770749417:9,143,218A/C—uncertain significance
rs156775018617:9,143,271T/C—pathogenic
rs156775018717:9,143,272G/C—pathogenic
rs37152105117:9,143,279G/A—likely benign
rs74692611417:9,143,280G/A—uncertain significance
rs250809338517:9,143,285G/A—likely benign

Gene information from NCBI Gene. Variant classifications from ClinVar.