rs7406226
This is a intron variant variant in the NTN1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Orofacial cleft
Leslie EJ et al. “A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13.” Human Molecular Genetics 25(13):2862-2872 (2016)
Allele A
OR 1.45
p 1.0e-8
N 1,096
Large GWAS
African unspecified
About NTN1
Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of netrin suggest that variation in netrin may be involved in cancer development. [provided by RefSeq, Jul 2008]
View all NTN1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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