RAB5B
RAB5B, member RAS oncogene family
Summary
Enables GDP binding activity; GTP-dependent protein binding activity; and GTPase activity. Involved in antigen processing and presentation and plasma membrane to endosome transport. Located in endosome and extracellular exosome. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants20 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs17528736 | 12:56,368,518 | C/T | downstream gene variant | — |
| rs773111 | 12:56,375,740 | C/A | upstream gene variant | — |
| rs1873914 | 12:56,379,427 | G/C | upstream gene variant | — |
| rs139121417 | 12:56,380,060 | C/T | intron variant | — |
| rs151173738 | 12:56,380,773 | A/G | — | uncertain significance |
| rs757683306 | 12:56,380,790 | A/G | — | uncertain significance |
| rs2540560923 | 12:56,383,850 | G/A | — | uncertain significance |
| rs2136490152 | 12:56,384,556 | G/C | — | uncertain significance |
| rs201470751 | 12:56,385,153 | G/C | — | uncertain significance |
| rs1890146196 | 12:56,385,905 | C/T | — | uncertain significance |
| rs978033745 | 12:56,385,910 | A/G | — | uncertain significance |
| rs772548927 | 12:56,385,954 | T/C | — | likely benign |
| rs11550558 | 12:56,386,076 | A/G | coding sequence variant | — |
| rs34962186 | 12:56,388,889 | T/A | — | — |
| rs705700 | 12:56,389,293 | T/C | regulatory region variant | — |
| rs58717357 | 12:56,389,565 | G/T | — | — |
| rs11171718 | 12:56,389,622 | G/A | downstream gene variant | — |
| rs60028217 | 12:56,389,789 | T/A | downstream gene variant | — |
| rs772920 | 12:56,390,364 | C/G | regulatory region variant | — |
| rs705702 | 12:56,390,636 | A/T | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.