Trait
SNPs associated with Rheumatoid Arthritis, Anti-Citrullinated Protein Antibody Seropositivity, Rheumatoid Factor Seropositivity Measurement
101 genetic variants across 39 genes have been associated with Rheumatoid Arthritis, Anti-Citrullinated Protein Antibody Seropositivity, Rheumatoid Factor Seropositivity Measurement in published research. Key genes include ANKRD55, C20orf181, CASP8.
Associated variants101 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs3093017 | — | GWAS association (p=4.0e-47) | Large GWAS |
| rs35926684 | — | GWAS association (p=7.0e-34) | Large GWAS |
| rs7731626 | ANKRD55 | GWAS association (p=4.0e-33) | Large GWAS |
| rs3087243 | CTLA4 | GWAS association (p=4.0e-28) | Large GWAS |
| rs11889341 | STAT4 | GWAS association (p=2.0e-26) | Large GWAS |
| rs12712065 | — | GWAS association (p=5.0e-26) | Large GWAS |
| rs2258734 | TNFRSF14 | GWAS association (p=2.0e-24) | Large GWAS |
| rs28362855 | NFKBIE | GWAS association (p=7.0e-24) | Large GWAS |
| rs7902146 | — | GWAS association (p=4.0e-23) | Large GWAS |
| rs8026898 | — | GWAS association (p=5.0e-23) | Large GWAS |
| rs2069235 | — | GWAS association (p=3.0e-20) | Large GWAS |
| rs6495979 | — | GWAS association (p=6.0e-20) | Large GWAS |
| rs3757387 | — | GWAS association (p=1.0e-19) | Large GWAS |
| rs2736340 | — | GWAS association (p=2.0e-19) | Large GWAS |
| rs74313386 | — | GWAS association (p=8.0e-19) | Large GWAS |
| rs34536443 | TYK2 | GWAS association (p=2.0e-18) | Large GWAS |
| rs9927316 | LOC124903741 | GWAS association (p=5.0e-18) | Large GWAS |
| rs9532434 | COG6 | GWAS association (p=6.0e-18) | Large GWAS |
| rs1883832 | CD40 | GWAS association (p=1.0e-17) | Large GWAS |
| rs55963299 | REL-DT | GWAS association (p=3.0e-17) | Large GWAS |
| rs2812378 | CCL21 | GWAS association (p=6.0e-16) | Large GWAS |
| rs3134883 | IL2RA | GWAS association (p=2.0e-15) | Large GWAS |
| rs798000 | — | GWAS association (p=4.0e-15) | Large GWAS |
| rs2485362 | — | GWAS association (p=6.0e-15) | Large GWAS |
| rs7241016 | — | GWAS association (p=6.0e-15) | Large GWAS |
| rs3804333 | — | GWAS association (p=7.0e-15) | Large GWAS |
| rs7540342 | — | GWAS association (p=4.0e-14) | Large GWAS |
| rs73005423 | — | GWAS association (p=6.0e-14) | Large GWAS |
| rs1885013 | RAD51B | GWAS association (p=7.0e-14) | Large GWAS |
| rs5019428 | PLCL2 | GWAS association (p=4.0e-13) | Large GWAS |
| rs1953126 | PHF19 | GWAS association (p=6.0e-13) | Large GWAS |
| rs56750287 | — | GWAS association (p=5.0e-12) | Large GWAS |
| rs6681482 | TNFSF4 | GWAS association (p=1.0e-11) | Large GWAS |
| rs793095 | LOC105376481 | GWAS association (p=1.0e-11) | Large GWAS |
| rs115284761 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs1893592 | UBASH3A | GWAS association (p=2.0e-11) | Large GWAS |
| rs2918392 | DAP | GWAS association (p=2.0e-11) | Large GWAS |
| rs187579 | MACIR | GWAS association (p=2.0e-11) | Large GWAS |
| rs2317231 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs10905284 | GATA3 | GWAS association (p=3.0e-11) | Large GWAS |
| rs7097397 | WDFY4 | GWAS association (p=1.0e-10) | Large GWAS |
| rs4409785 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs2141331 | CASP8 | GWAS association (p=1.0e-10) | Large GWAS |
| rs2664035 | TEC | GWAS association (p=1.0e-10) | Large GWAS |
| rs10175798 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs10497813 | PLCL1 | GWAS association (p=2.0e-10) | Large GWAS |
| rs6831973 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs7171617 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs4690029 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs66922517 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs5754100 | UBE2L3 | GWAS association (p=3.0e-10) | Large GWAS |
| rs11777380 | — | GWAS association (p=4.0e-10) | Large GWAS |
| rs42044 | — | GWAS association (p=4.0e-10) | Large GWAS |
| rs705700 | RAB5B | GWAS association (p=4.0e-10) | Large GWAS |
| rs4655698 | IL12RB2 | GWAS association (p=6.0e-10) | Large GWAS |
| rs10453119 | LOC105375920 | GWAS association (p=7.0e-10) | Large GWAS |
| rs1264600 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs4809371 | C20orf181 | GWAS association (p=2.0e-09) | Large GWAS |
| rs12530098 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs12519914 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs7943728 | MYRF | GWAS association (p=2.0e-09) | Large GWAS |
| rs11420145 | — | GWAS association (p=3.0e-09) | Large GWAS |
| rs16903108 | — | GWAS association (p=3.0e-09) | Large GWAS |
| rs6930468 | — | GWAS association (p=3.0e-09) | Large GWAS |
| rs182199544 | — | GWAS association (p=5.0e-09) | Large GWAS |
| rs61944750 | FLT3 | GWAS association (p=5.0e-09) | Large GWAS |
| rs3184504 | SH2B3 | GWAS association (p=1.0e-08) | Large GWAS |
| rs1696466 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs41313373 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs67318457 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs10556591 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs940825 | LOC101927609 | GWAS association (p=1.0e-08) | Large GWAS |
| rs55762233 | HAPLN4 | GWAS association (p=2.0e-08) | Large GWAS |
| rs9826420 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs113532504 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs34480360 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs143259280 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs6814280 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs1422673 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs2300373 | IFNGR2 | GWAS association (p=2.0e-08) | Large GWAS |
| rs911760 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs2147161 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs244468 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs8106598 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs591549 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs734094 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs12145329 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs41269479 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs11375064 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs4687070 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs10917571 | FCGR3A | GWAS association (p=5.0e-08) | Large GWAS |
| rs2476601 | PTPN22 | GWAS association (p=5.0e-174) | Large GWAS |
| rs575378713 | — | GWAS association (p=2.0e-22) | Large GWAS |
| rs11454989 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs77574423 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs9880772 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs3001423 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs4584833 | TXNDC11 | GWAS association (p=1.0e-10) | Large GWAS |
| rs9269234 | — | GWAS association (p=6.0e-16) | Small GWAS |
| rs12601925 | — | GWAS association (p=6.0e-09) | Small GWAS |
Showing the top 100 of 101 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.