rs3774354
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
total hip arthroplasty, osteoarthritis
Boer CG et al. “Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.” Cell 184(18):4784-4818.e17 (2021)
Allele A
OR 1.10
p 1.0e-16
N 319,037
Large GWAS
European
osteoarthritis, hip
Henkel C et al. “Genome-wide association meta-analysis of knee and hip osteoarthritis uncovers genetic differences between patients treated with joint replacement and patients without joint replacement.” Annals of the Rheumatic Diseases 82(3):384-392 (2023)
Allele A
OR 1.08
p 7.0e-12
N 646,831
Meta-analysisLarge GWAS
European
osteoarthritis, hip, osteoarthritis, knee
Tachmazidou I et al. “Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.” Nature Genetics 51(2):230-236 (2019)
Allele A
OR 1.06
p 1.0e-11
N 417,596
Major Consortium StudyLarge GWAS
European
memory performance
Lahti J et al. “Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.” Molecular Psychiatry 27(11):4419-4431 (2022)
Allele A
OR 5.77
p 8.0e-9
N 28,909
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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