Trait
SNPs associated with Osteoarthritis, Hip, Osteoarthritis, Knee
167 genetic variants across 42 genes have been associated with Osteoarthritis, Hip, Osteoarthritis, Knee in published research. Key genes include ACAN, APOE, BCAS3.
Associated variants167 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs547181612 | — | GWAS association (p=1.0e-16) | Major Consortium Study |
| rs4979341 | — | GWAS association (p=3.0e-16) | Major Consortium Study |
| rs3821262 | — | GWAS association (p=4.0e-13) | Major Consortium Study |
| rs4630744 | — | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs75621460 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs3774354 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs2820443 | — | GWAS association (p=6.0e-11) | Major Consortium Study |
| rs17659798 | — | GWAS association (p=2.0e-10) | Major Consortium Study |
| rs9277552 | HLA-DPB1 | GWAS association (p=2.0e-10) | Major Consortium Study |
| rs6976 | GNL3 | GWAS association (p=2.0e-10) | Major Consortium Study |
| rs2953013 | — | GWAS association (p=3.0e-10) | Major Consortium Study |
| rs11997261 | — | GWAS association (p=5.0e-10) | Major Consortium Study |
| rs3884606 | FGF18 | GWAS association (p=9.0e-10) | Major Consortium Study |
| rs11732213 | SLBP | GWAS association (p=9.0e-10) | Major Consortium Study |
| rs4144502 | CRADD | GWAS association (p=9.0e-10) | Major Consortium Study |
| rs11456119 | — | GWAS association (p=1.0e-09) | Major Consortium Study |
| rs9930333 | FTO | GWAS association (p=2.0e-09) | Major Consortium Study |
| rs2622873 | — | GWAS association (p=2.0e-09) | Major Consortium Study |
| rs9977881 | — | GWAS association (p=3.0e-09) | Major Consortium Study |
| rs2820436 | LYPLAL1-AS1 | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs10492367 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs11105466 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs200975846 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs12470967 | LOC729254 | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs12193102 | SUPT3H | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs10758594 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs11075989 | FTO | GWAS association (p=1.0e-34) | Large GWAS |
| rs1851610 | TGFA | GWAS association (p=4.0e-28) | Large GWAS |
| rs6060401 | — | GWAS association (p=5.0e-28) | Large GWAS |
| rs12509303 | — | GWAS association (p=3.0e-25) | Large GWAS |
| rs429358 | APOE | GWAS association (p=1.0e-24) | Large GWAS |
| rs11130325 | NEK4 | GWAS association (p=9.0e-21) | Large GWAS |
| rs3910146 | LOC124900668 | GWAS association (p=2.0e-20) | Large GWAS |
| rs34049648 | — | GWAS association (p=2.0e-20) | Large GWAS |
| rs10771027 | — | GWAS association (p=6.0e-20) | Large GWAS |
| rs2605111 | — | GWAS association (p=9.0e-20) | Large GWAS |
| rs2716212 | — | GWAS association (p=4.0e-19) | Large GWAS |
| rs56283067 | — | GWAS association (p=9.0e-19) | Large GWAS |
| rs9940278 | FTO | GWAS association (p=1.0e-18) | Large GWAS |
| rs13107325 | SLC39A8 | GWAS association (p=1.0e-17) | Large GWAS |
| rs12901372 | — | GWAS association (p=7.0e-17) | Large GWAS |
| rs7020944 | PAPPA | GWAS association (p=1.0e-16) | Large GWAS |
| rs10846653 | — | GWAS association (p=4.0e-16) | Large GWAS |
| rs7572753 | — | GWAS association (p=5.0e-16) | Large GWAS |
| rs10974438 | — | GWAS association (p=6.0e-16) | Large GWAS |
| rs2205325 | LOC105372740 | GWAS association (p=7.0e-16) | Large GWAS |
| rs4606747 | — | GWAS association (p=2.0e-15) | Large GWAS |
| rs34862454 | — | GWAS association (p=6.0e-15) | Large GWAS |
| rs963292 | — | GWAS association (p=7.0e-15) | Large GWAS |
| rs9462027 | — | GWAS association (p=1.0e-14) | Large GWAS |
| rs6488868 | — | GWAS association (p=4.0e-14) | Large GWAS |
| rs11001784 | — | GWAS association (p=7.0e-14) | Large GWAS |
| rs10048129 | WWP2 | GWAS association (p=8.0e-14) | Large GWAS |
| rs10131337 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs10831477 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs1325032 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs77165542 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs2148677 | — | GWAS association (p=2.0e-13) | Large GWAS |
| rs12212816 | — | GWAS association (p=3.0e-13) | Large GWAS |
| rs76078245 | — | GWAS association (p=4.0e-13) | Large GWAS |
| rs72760655 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs876122 | — | GWAS association (p=7.0e-13) | Large GWAS |
| rs4764133 | — | GWAS association (p=8.0e-13) | Large GWAS |
| rs849138 | — | GWAS association (p=8.0e-13) | Large GWAS |
| rs6457804 | — | GWAS association (p=9.0e-13) | Large GWAS |
| rs1964521 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs2171125 | CRADD | GWAS association (p=2.0e-12) | Large GWAS |
| rs9533090 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs2236295 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs2867109 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs111333168 | LOC105376205 | GWAS association (p=4.0e-12) | Large GWAS |
| rs113379345 | LOC112268150 | GWAS association (p=4.0e-12) | Large GWAS |
| rs7953280 | — | GWAS association (p=5.0e-12) | Large GWAS |
| rs74767794 | — | GWAS association (p=5.0e-12) | Large GWAS |
| rs28510415 | PTCH1 | GWAS association (p=7.0e-12) | Large GWAS |
| rs3118919 | — | GWAS association (p=7.0e-12) | Large GWAS |
| rs62070652 | — | GWAS association (p=8.0e-12) | Large GWAS |
| rs4974126 | ERC2 | GWAS association (p=1.0e-11) | Large GWAS |
| rs146939415 | CYP19A1 | GWAS association (p=1.0e-11) | Large GWAS |
| rs28579874 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs10843013 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs56294732 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs1999659 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs11209943 | LOC105378797 | GWAS association (p=3.0e-11) | Large GWAS |
| rs8096658 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs9908159 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs17615906 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs2163832 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs7581446 | LTBP1 | GWAS association (p=5.0e-11) | Large GWAS |
| rs7792176 | — | GWAS association (p=5.0e-11) | Large GWAS |
| rs26023 | FBN2 | GWAS association (p=5.0e-11) | Large GWAS |
| rs12139120 | — | GWAS association (p=6.0e-11) | Large GWAS |
| rs227732 | — | GWAS association (p=7.0e-11) | Large GWAS |
| rs6117276 | — | GWAS association (p=9.0e-11) | Large GWAS |
| rs72799234 | GPR75-ASB3 | GWAS association (p=9.0e-11) | Large GWAS |
| rs9429754 | — | GWAS association (p=9.0e-11) | Large GWAS |
| rs12129705 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs1426371 | WSCD2 | GWAS association (p=1.0e-10) | Large GWAS |
| rs7189660 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs270397 | — | GWAS association (p=1.0e-10) | Large GWAS |
Showing the top 100 of 167 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.