rs77165542
▶GWAS Catalog Trait Associations (8)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (8)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
urate measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.03
p 1.0e-14
N 394,642
Large GWAS
European
osteoarthritis, hip, osteoarthritis, knee
Hatzikotoulas K et al. “Translational genomics of osteoarthritis in 1,962,069 individuals.” Nature 641(8065):1217-1224 (2025)
Allele T
OR 0.91
p 1.0e-13
N 1,294,321
Large GWAS
multi-ancestry
osteoarthritis
Hatzikotoulas K et al. “Translational genomics of osteoarthritis in 1,962,069 individuals.” Nature 641(8065):1217-1224 (2025)
Allele T
OR 0.94
p 2.0e-11
N 1,962,069
Large GWAS
multi-ancestry
alcohol consumption quality
Liu M et al. “Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.” Nature Genetics 51(2):237-244 (2019)
Allele T
OR 0.03
p 6.0e-11
N 941,280
Large GWAS
European
osteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty
Hatzikotoulas K et al. “Translational genomics of osteoarthritis in 1,962,069 individuals.” Nature 641(8065):1217-1224 (2025)
Allele T
OR 0.89
p 6.0e-11
N 866,417
Large GWAS
multi-ancestry
osteoarthritis, knee
Hatzikotoulas K et al. “Translational genomics of osteoarthritis in 1,962,069 individuals.” Nature 641(8065):1217-1224 (2025)
Allele T
OR 0.92
p 2.0e-10
N 1,316,500
Large GWAS
multi-ancestry
body mass index
Helgeland Ø et al. “Characterization of the genetic architecture of infant and early childhood body mass index.” Nature Metabolism 4(3):344-358 (2022)
Allele C
OR 0.19
p 4.0e-9
N 21,871
Large GWAS
European
anxiety measurement
Hill WD et al. “Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.” Molecular Psychiatry 25(11):3034-3052 (2020)
Allele C
OR 0.01
p 5.0e-8
N 270,059
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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