rs10131337

GWAS Catalog Trait Associations (7)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body height

Allele T
OR 0.02
p 2.0e-198
N 5,314,291
Large GWAS
European, Hispanic or Latin American, East Asian, African unspecified, South Asian
Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele T
OR 0.04
p 1.0e-18
N 607,510
Major Consortium StudyLarge GWAS
multi-ancestry
Allele T
OR 0.01
p 7.0e-22
N 405,540
Large GWAS
European
Allele T
OR 0.01
p 3.0e-21
N 394,642
Large GWAS
European

osteoarthritis, knee

Hatzikotoulas K et al. Translational genomics of osteoarthritis in 1,962,069 individuals. Nature 641(8065):1217-1224 (2025)
Allele T
OR 0.95
p 9.0e-23
N 1,316,500
Large GWAS
multi-ancestry

osteoarthritis, knee, total knee arthroplasty

Hatzikotoulas K et al. Translational genomics of osteoarthritis in 1,962,069 individuals. Nature 641(8065):1217-1224 (2025)
Allele T
OR 0.93
p 2.0e-17
N 1,006,624
Large GWAS
multi-ancestry

osteoarthritis, hip, osteoarthritis, knee

Hatzikotoulas K et al. Translational genomics of osteoarthritis in 1,962,069 individuals. Nature 641(8065):1217-1224 (2025)
Allele T
OR 0.97
p 1.0e-13
N 1,294,321
Large GWAS
multi-ancestry

health trait

Allele C
OR 0.01
p 5.0e-12
N 405,979
Large GWAS
European

body weight

Allele T
OR 0.01
p 6.0e-11
N 928,679
Large GWAS
multi-ancestry

osteoarthritis

Hatzikotoulas K et al. Translational genomics of osteoarthritis in 1,962,069 individuals. Nature 641(8065):1217-1224 (2025)
Allele T
OR 0.98
p 4.0e-10
N 1,962,069
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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