rs3788042

This is a intron variant variant in the PKNOX1 gene.

▶

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

gut microbiome measurement

Dekkers KF et al. “Genome-wide association analyses highlight the role of the intestinal molecular environment in human gut microbiota variation.” Nature Genetics 58(3):540-549 (2026)

Allele A

OR 0.10

p 4.0e-8

N 16,017

Large GWAS

European

About PKNOX1

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in angiogenesis. Predicted to act upstream of or within camera-type eye development; hemopoiesis; and positive regulation of transcription by RNA polymerase II. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all PKNOX1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Loading comments…