rs3802241
This is a intron variant variant in the ADRA1A gene.
▶Research that mentions this SNP (1)
▶The correlation between SNPs within the gene of adrenergic receptor and neuropeptide Y and risk of cervical vertigoAssociationN=420Jianlong Han et al.(2018)· Journal of Clinical Laboratory Analysis
Case-control study of 216 cervical vertigo patients and 204 controls identifying SNPs in ADRA1A, ADRB1, ADRB2, and NPY genes significantly associated with cervical vertigo risk (ORs 0.62-2.07) and clinical prognosis markers (JOA score and recovery rate). ADRA1A rs3802241 showed OR=2.07 for disease risk and protective effect on prognosis; NPY variants predicted recovery outcomes.
About ADRA1A
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]
View all ADRA1A variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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