rs3813579
This variant is located in the LOC105371356 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Thyroid stimulating hormone level
Williams AT et al. “Genome-wide association study of thyroid-stimulating hormone highlights new genes, pathways and associations with thyroid disease.” Nature Communications 14(1):6713 (2023)
Allele A
OR 0.07
p 2.0e-193
N 247,107
Large GWAS
multi-ancestry
Wei Y et al. “Genome-wide association studies of thyroid-related hormones, dysfunction, and autoimmunity among 85,421 Chinese pregnancies.” Nature Communications 15(1):8004 (2024)
Allele A
OR 0.12
p 2.0e-58
N 67,471
Large GWAS
East Asian
Jacobs BM et al. “Genetic architecture of routinely acquired blood tests in a British South Asian cohort.” Nature Communications 15(1):8929 (2024)
Allele A
OR 0.06
p 4.0e-16
N 38,000
Large GWAS
South Asian
hypothyroidism
Wei Y et al. “Genome-wide association studies of thyroid-related hormones, dysfunction, and autoimmunity among 85,421 Chinese pregnancies.” Nature Communications 15(1):8004 (2024)
Allele G
OR 1.26
p 2.0e-14
N 73,050
Large GWAS
East Asian
thyroid gland volume
Teumer A et al. “Genome-wide association study identifies four genetic loci associated with thyroid volume and goiter risk.” American Journal of Human Genetics 88(5):664-73 (2011)
Allele A
OR 1.32
p 4.0e-10
N 3,620
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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