rs41280589
This variant is located in the REV1 gene.
▶ClinVar annotation
Benign★★★☆
2 submitters2 publicationsAbout REV1
This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. [provided by RefSeq, Mar 2016]
View all REV1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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