rs41306688
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
PR interval
Ntalla I et al. “Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.” Nature Communications 11(1):2542 (2020)
Allele C
OR 1.65
p 4.0e-19
N 292,566
Large GWAS
multi-ancestry
hypertrophic cardiomyopathy
Tadros R et al. “Large-scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy.” Nature Genetics 57(3):530-538 (2025)
Allele C
OR 0.47
p 9.0e-18
N 28,106
Large GWAS
European, African unspecified, Hispanic or Latin American, East Asian, South Asian, NR
Harper AR et al. “Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity.” Nature Genetics 53(2):135-142 (2021)
Allele C
OR 0.63
p 4.0e-9
N 29,218
Large GWAS
multi-ancestry
QRS-T angle
Young WJ et al. “Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease.” Nature Communications 14(1):1411 (2023)
Allele A
OR 0.10
p 7.0e-12
N 96,562
Large GWAS
European
atrial fibrillation
Roselli C et al. “Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases.” Nature Genetics 57(3):539-547 (2025)
Allele C
OR 1.07
p 2.0e-8
N 1,650,345
Meta-analysisLarge GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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