rs4444878

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GWAS Catalog Trait Associations (6)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

pulmonary embolism, Pulmonary Infarction

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.25
p 3.0e-64
N 447,859
Major Consortium StudyLarge GWAS
European

cardioembolic stroke

Mishra A et al. “Stroke genetics informs drug discovery and risk prediction across ancestries.” Nature 611(7934):115-123 (2022)
Allele A
OR 1.10
p 1.0e-10
N 1,516,688
Large GWAS
multi-ancestry
Malik R et al. “Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.” Nature Genetics 50(4):524-537 (2018)
Allele A
OR 1.10
p 5.0e-8
N 415,547
Large GWAS
multi-ancestry

deep vein thrombosis

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.21
p 3.0e-50
N 400,487
Major Consortium StudyLarge GWAS
multi-ancestry

drug use measurement, deep vein thrombosis

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.18
p 5.0e-29
N 400,487
Major Consortium StudyLarge GWAS
multi-ancestry

heart disease

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.14
p 1.0e-44
N 437,454
Major Consortium StudyLarge GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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