rs4448201
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
femoral neck bone mineral density
Pei YF et al. “Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.” Bone 110:378-385 (2018)
Allele C
OR 0.07
p 3.0e-20
N 40,491
Large GWAS
multi-ancestry
spine bone mineral density
Pei YF et al. “Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.” Bone 110:378-385 (2018)
Allele C
OR 0.06
p 1.0e-11
N 40,491
Large GWAS
multi-ancestry
body composition measurement
Wu Z et al. “Genetic architecture of bone marrow fat fraction implies its involvement in osteoporosis risk.” Nature Communications 16(1):7490 (2025)
Allele G
OR 0.05
p 3.0e-10
N 38,559
Large GWAS
European
osteoporosis
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele C
OR 0.08
p 4.0e-8
N 667,227
Large GWAS
multi-ancestry
adipose amount
Ahmed A et al. “MRI-Based Genetic Studies Reveal Specific Genetic Variants and Disease Risks Associated With Fat Distribution Across Anatomical Sites.” Journal of Obesity 2025:7792701 (2025)
Allele G
OR 0.05
p 2.0e-12
N 37,589
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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