rs454214
This variant is located in the MEF2C-AS2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
major depressive disorder
Hyde CL et al. “Identification of 15 genetic loci associated with risk of major depression in individuals of European descent.” Nature Genetics 48(9):1031-6 (2016)
Allele T
OR 0.03
p 1.0e-9
N 326,113
Large GWAS
European
Nagel M et al. “Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.” Nature Genetics 50(7):920-927 (2018)
Allele T
OR 5.49
p 4.0e-8
N 688,809
Meta-analysisLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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