rs4575098
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
monocyte percentage of leukocytes
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.02
p 5.0e-28
N 394,642
Large GWAS
European
Vuckovic D et al. “The Polygenic and Monogenic Basis of Blood Traits and Diseases.” Cell 182(5):1214-1231.e11 (2020)
Allele A
OR 0.02
p 7.0e-21
N 408,112
Large GWAS
European
Astle WJ et al. “The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.” Cell 167(5):1415-1429.e19 (2016)
Allele A
OR 0.03
p 6.0e-11
N 170,494
Large GWAS
European
Alzheimer disease, waist-hip ratio
Bone WP et al. “Multi-trait association studies discover pleiotropic loci between Alzheimer's disease and cardiometabolic traits.” Alzheimer's Research & Therapy 13(1):34 (2021)
Allele A
OR —
p 4.0e-13
N 1,104,907
Large GWAS
Alzheimer disease, family history of Alzheimer’s disease
Jansen IE et al. “Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.” Nature Genetics 51(3):404-413 (2019)
Allele A
OR 6.36
p 2.0e-10
N 455,258
Meta-analysisLarge GWAS
European
Alzheimer disease
Lake J et al. “Multi-ancestry meta-analysis and fine-mapping in Alzheimer's disease.” Molecular Psychiatry 28(7):3121-3132 (2023)
Allele A
OR —
p 2.0e-8
N 644,188
Meta-analysisLarge GWAS
multi-ancestry
Koskeridis F et al. “Multi-trait association analysis reveals shared genetic loci between Alzheimer's disease and cardiovascular traits.” Nature Communications 15(1):9827 (2024)
Allele A
OR 0.01
p 3.0e-8
N 640,258
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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