rs4651103
This is a intron variant variant in the RABGAP1L gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
osteoarthritis
McDonald MN et al. “Novel genetic loci associated with osteoarthritis in multi-ancestry analyses in the Million Veteran Program and UK Biobank.” Nature Genetics 54(12):1816-1826 (2022)
Allele A
OR 1.01
p 9.0e-9
N 2,421,870
Major Consortium StudyLarge GWAS
European, South Asian, East Asian, African unspecified, Hispanic or Latin American
About RABGAP1L
Enables GTPase activator activity and small GTPase binding activity. Acts upstream of or within regulation of protein localization. Located in several cellular components, including Golgi apparatus; cilium; and early endosome. [provided by Alliance of Genome Resources, Jul 2025]
View all RABGAP1L variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…