rs4665630
This variant is located in the KLHL29 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
HbA1c measurement
Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele T
OR 0.02
p 3.0e-9
N 338,919
Major Consortium StudyLarge GWAS
multi-ancestry
generalised epilepsy
“Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies.” Nature Communications 9(1):5269 (2018)
Allele C
OR 5.48
p 4.0e-8
N 30,571
Large GWAS
multi-ancestry
About KLHL29
Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
View all KLHL29 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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