rs4703889
This variant is located in the ZNF366 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
monocyte count
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.03
p 2.0e-14
N 374,014
Major Consortium StudyLarge GWAS
multi-ancestry
tubulointerstitial nephritis antigen-like measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele C
OR 0.06
p 3.0e-12
N 47,745
Large GWAS
European
About ZNF366
Enables nuclear estrogen receptor binding activity and transcription corepressor activity. Involved in negative regulation of intracellular estrogen receptor signaling pathway; negative regulation of transcription by RNA polymerase II; and response to estrogen. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
View all ZNF366 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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