ZNF366
zinc finger protein 366
Summary
Enables nuclear estrogen receptor binding activity and transcription corepressor activity. Involved in negative regulation of intracellular estrogen receptor signaling pathway; negative regulation of transcription by RNA polymerase II; and response to estrogen. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants61 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs758115238 | 5:71,739,590 | C/T | — | uncertain significance |
| rs2479179092 | 5:71,739,716 | C/T | — | uncertain significance |
| rs959288227 | 5:71,739,720 | G/C | — | uncertain significance |
| rs777661372 | 5:71,739,735 | C/T | — | uncertain significance |
| rs80030847 | 5:71,739,798 | C/T | — | uncertain significance |
| rs112462947 | 5:71,739,855 | C/T | — | uncertain significance |
| rs541442537 | 5:71,739,930 | G/C | — | uncertain significance |
| rs752231269 | 5:71,739,986 | G/A | — | uncertain significance |
| rs757501081 | 5:71,739,996 | C/T | — | uncertain significance |
| rs2479179496 | 5:71,740,006 | G/T | — | uncertain significance |
| rs1363263603 | 5:71,740,056 | C/G | — | uncertain significance |
| rs748360938 | 5:71,740,080 | C/T | — | uncertain significance |
| rs1742917243 | 5:71,740,106 | C/T | — | uncertain significance |
| rs6452471 | 5:71,741,012 | C/T | — | — |
| rs7709477 | 5:71,741,282 | C/T | upstream gene variant | — |
| rs6859727 | 5:71,742,622 | T/C | upstream gene variant | — |
| rs10043295 | 5:71,743,024 | G/C | upstream gene variant | — |
| rs145476513 | 5:71,743,097 | C/T | — | uncertain significance |
| rs771244069 | 5:71,743,099 | C/T | — | uncertain significance |
| rs555104690 | 5:71,743,208 | T/C | — | uncertain significance |
| rs4703889 | 5:71,747,906 | G/A | — | — |
| rs745560582 | 5:71,752,322 | T/C | — | uncertain significance |
| rs1466961228 | 5:71,752,332 | G/A | — | uncertain significance |
| rs146052499 | 5:71,756,005 | G/A | — | uncertain significance |
| rs2479189859 | 5:71,756,070 | G/C | — | uncertain significance |
| rs2479190093 | 5:71,756,255 | C/T | — | uncertain significance |
| rs757583639 | 5:71,756,293 | C/T | — | uncertain significance |
| rs1351594899 | 5:71,756,294 | G/A | — | uncertain significance |
| rs2479190146 | 5:71,756,308 | C/A | — | uncertain significance |
| rs1377428535 | 5:71,756,337 | C/T | — | uncertain significance |
| rs773713314 | 5:71,756,447 | G/T | — | uncertain significance |
| rs1476531153 | 5:71,756,465 | C/T | — | uncertain significance |
| rs142021145 | 5:71,756,519 | C/A | missense variant | — |
| rs372293606 | 5:71,756,549 | C/T | — | uncertain significance |
| rs1561193820 | 5:71,756,584 | C/T | — | uncertain significance |
| rs2479190557 | 5:71,756,585 | C/A | — | uncertain significance |
| rs372122906 | 5:71,756,647 | T/C | — | uncertain significance |
| rs202206020 | 5:71,756,654 | C/G | — | uncertain significance |
| rs746514644 | 5:71,756,696 | C/T | — | uncertain significance |
| rs2479190705 | 5:71,756,710 | G/C | — | uncertain significance |
| rs144891537 | 5:71,756,726 | G/A | — | uncertain significance |
| rs751455288 | 5:71,756,822 | G/C | — | uncertain significance |
| rs539423696 | 5:71,756,890 | A/T | — | uncertain significance |
| rs543126714 | 5:71,756,901 | G/T | — | uncertain significance |
| rs150204419 | 5:71,756,906 | G/A | — | uncertain significance |
| rs948018933 | 5:71,756,941 | A/C | — | uncertain significance |
| rs145676992 | 5:71,756,974 | G/C | — | uncertain significance |
| rs759062964 | 5:71,757,013 | T/C | — | likely benign |
| rs1474430891 | 5:71,757,017 | C/T | — | uncertain significance |
| rs1743305179 | 5:71,757,029 | G/A | — | uncertain significance |
| rs751855631 | 5:71,757,032 | C/T | — | uncertain significance |
| rs766500674 | 5:71,757,046 | T/G | — | uncertain significance |
| rs148388764 | 5:71,757,054 | G/T | — | uncertain significance |
| rs141570744 | 5:71,757,106 | C/T | — | uncertain significance |
| rs753860951 | 5:71,757,140 | C/T | — | uncertain significance |
| rs1329196470 | 5:71,757,214 | T/G | — | uncertain significance |
| rs752807960 | 5:71,757,304 | A/T | — | uncertain significance |
| rs141028968 | 5:71,760,635 | C/T | regulatory region variant | — |
| rs11738874 | 5:71,782,894 | G/T | — | — |
| rs116159540 | 5:71,783,430 | A/G | regulatory region variant | — |
| rs10462395 | 5:71,783,992 | A/G | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.