rs4767549
This is a intron variant variant in the KSR2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
PCSK9 protein measurement
Pott J et al. “Sex and statin-related genetic associations at the PCSK9 gene locus: results of genome-wide association meta-analysis.” Biology of Sex Differences 15(1):26 (2024)
Allele T
OR 0.02
p 1.0e-8
N 11,080
Meta-analysisLarge GWAS
European
About KSR2
Enables protein serine/threonine kinase activity. Predicted to be involved in Ras protein signal transduction; calcium-mediated signaling; and positive regulation of cold-induced thermogenesis. Predicted to act upstream of or within positive regulation of MAPK cascade. Predicted to be located in membrane. Predicted to be active in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all KSR2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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