rs4836726

This variant is located in the ASTN2 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

subiculum volume

van der Meer D et al. “Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes.” Molecular Psychiatry 25(11):3053-3065 (2020)

Allele G

OR 5.65

p 3.0e-11

N 21,297

Large GWAS

European

About ASTN2

This gene encodes a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mouse. A deletion at this locus has been associated with schizophrenia. Multiple transcript variants encoding different proteins have been found for this locus. [provided by RefSeq, May 2010]

View all ASTN2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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