rs4848197

This variant is located in the ANAPC1 gene.

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ClinVar annotation

Benign★★★☆

3 submitters1 publication

Rothmund-Thomson syndrome type 1; not provided; Melanoma; Familial cancer of breast

About ANAPC1

This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011]

View all ANAPC1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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