rs4936277
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
neuroticism measurement
Hill WD et al. “Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.” Molecular Psychiatry 25(11):3034-3052 (2020)
Allele A
OR 0.01
p 3.0e-12
N 270,059
Large GWAS
European
Baselmans BML et al. “Multivariate genome-wide analyses of the well-being spectrum.” Nature Genetics 51(3):445-451 (2019)
Allele A
OR 0.01
p 9.0e-10
N 523,783
Large GWAS
European
self reported educational attainment
Lee JJ et al. “Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.” Nature Genetics 50(8):1112-1121 (2018)
Allele A
OR 0.01
p 7.0e-12
N 1,311,438
Large GWAS
European
depressive symptom measurement
Baselmans BML et al. “Multivariate genome-wide analyses of the well-being spectrum.” Nature Genetics 51(3):445-451 (2019)
Allele G
OR 0.01
p 2.0e-9
N 1,067,913
Large GWAS
European
alcohol use disorder measurement, alcohol dependence
Kranzler HR et al. “Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.” Nature Communications 10(1):1499 (2019)
Allele A
OR 1.06
p 3.0e-11
N 274,391
Large GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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