rs4937872
▶GWAS Catalog Trait Associations (7)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (7)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
irritable bowel syndrome
Alemany S et al. “Genome-wide multi-trait analysis of irritable bowel syndrome and related mental conditions identifies 38 new independent variants.” Journal of Translational Medicine 21(1):272 (2023)
Allele A
OR 0.01
p 7.0e-15
N 887,490
Large GWAS
European
anxiety measurement
Thorp JG et al. “Symptom-level modelling unravels the shared genetic architecture of anxiety and depression.” Nature Human Behaviour 5(10):1432-1442 (2021)
Allele A
OR 0.02
p 2.0e-14
N 136,957
Large GWAS
European
feeling tense measurement
Nagel M et al. “Item-level analyses reveal genetic heterogeneity in neuroticism.” Nature Communications 9(1):905 (2018)
Allele A
OR 6.57
p 5.0e-11
N 371,318
Large GWAS
European
Anxiety
Nagel M et al. “Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.” Nature Genetics 50(7):920-927 (2018)
Allele G
OR 0.01
p 1.0e-9
N 348,219
Meta-analysisLarge GWAS
European
brain injury
Merritt VC et al. “Genome-wide association study of traumatic brain injury in U.S. military veterans enrolled in the VA million veteran program.” Molecular Psychiatry 29(1):97-111 (2024)
Allele G
OR 1.04
p 1.0e-9
N 232,275
Major Consortium StudyLarge GWAS
European
major depressive disorder
Als TD et al. “Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses.” Nature Medicine 29(7):1832-1844 (2023)
Allele A
OR 0.02
p 1.0e-9
N 1,349,887
Large GWAS
European
post-traumatic stress disorder
Wendt FR et al. “Using phenotype risk scores to enhance gene discovery for generalized anxiety disorder and posttraumatic stress disorder.” Molecular Psychiatry 27(4):2206-2215 (2022)
Allele A
OR 0.01
p 4.0e-9
N 497,803
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…