rs4944958
This is a upstream gene variant variant in the NADSYN1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
vitamin D deficiency
Amin HA et al. “No evidence that vitamin D is able to prevent or affect the severity of COVID-19 in individuals with European ancestry: a Mendelian randomisation study of open data.” Bmj Nutrition, Prevention & Health 4(1):42-48 (2021)
Allele A
OR 0.26
p 9.0e-143
N 175,977
Large GWAS
European
About NADSYN1
Nicotinamide adenine dinucleotide (NAD) is a coenzyme in metabolic redox reactions, a precursor for several cell signaling molecules, and a substrate for protein posttranslational modifications. NAD synthetase (EC 6.3.5.1) catalyzes the final step in the biosynthesis of NAD from nicotinic acid adenine dinucleotide (NaAD).[supplied by OMIM, Apr 2004]
View all NADSYN1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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