Trait
SNPs associated with Vitamin D deficiency
36 genetic variants across 13 genes have been associated with Vitamin D deficiency in published research. Key genes include APOA5, CYP2R1, DHCR7.
Associated variants36 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs10741657 | CYP2R1 | Increased risk of vitamin D deficiency | Meta-analysis |
| rs1352846 | GC | GWAS association (p=2.0e-212) | Major Consortium Study |
| rs117913124 | CYP2R1 | GWAS association (p=2.0e-139) | Major Consortium Study |
| rs3750997 | DHCR7 | GWAS association (p=6.0e-29) | Major Consortium Study |
| rs4588 | GC | GWAS association (p=1.0e-17) | Major Consortium Study |
| rs12794714 | CYP2R1 | GWAS association (p=2.0e-16) | Major Consortium Study |
| rs17868335 | UGT1A10 | GWAS association (p=5.0e-15) | Major Consortium Study |
| rs2282679 | GC | GWAS association (p=1.0e-200) | Large GWAS |
| rs4944958 | NADSYN1 | GWAS association (p=9.0e-143) | Large GWAS |
| rs10859995 | — | GWAS association (p=3.0e-33) | Large GWAS |
| rs7129781 | CYP2R1 | GWAS association (p=4.0e-33) | Large GWAS |
| rs12123821 | — | GWAS association (p=6.0e-26) | Large GWAS |
| rs10426201 | — | GWAS association (p=8.0e-20) | Large GWAS |
| rs17217119 | — | GWAS association (p=5.0e-16) | Large GWAS |
| rs6600893 | — | GWAS association (p=5.0e-15) | Large GWAS |
| rs964184 | APOA5 | GWAS association (p=3.0e-14) | Large GWAS |
| rs1268647997 | RDH13 | GWAS association (p=2.0e-12) | Large GWAS |
| rs62122090 | HS1BP3 | GWAS association (p=2.0e-12) | Large GWAS |
| rs1185902565 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs952825245 | SLC25A37 | GWAS association (p=5.0e-12) | Large GWAS |
| rs3755322 | — | GWAS association (p=6.0e-12) | Large GWAS |
| rs150425221 | LOC105369890 | GWAS association (p=6.0e-12) | Large GWAS |
| rs143313202 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs73195003 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs140599862 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs2205262 | — | GWAS association (p=5.0e-11) | Large GWAS |
| rs73776179 | LAMA2 | GWAS association (p=5.0e-11) | Large GWAS |
| rs1454700296 | — | GWAS association (p=7.0e-11) | Large GWAS |
| rs867934853 | — | GWAS association (p=9.0e-11) | Large GWAS |
| rs563431181 | PXK | GWAS association (p=9.0e-11) | Large GWAS |
| rs1800588 | LIPC | GWAS association (p=2.0e-10) | Large GWAS |
| rs3750297 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs4845491 | — | GWAS association (p=7.0e-10) | Large GWAS |
| rs55791371 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs1532085 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs8123293 | — | GWAS association (p=3.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.