rs55791371

This is a intergenic variant variant.

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

coronary artery disease

van der Harst P et al. “Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.” Circulation Research 122(3):433-443 (2018)

Allele A

OR 0.12

p 2.0e-36

N 547,261

Large GWAS

total cholesterol measurement

Yin X et al. “Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.” Nature Communications 13(1):1644 (2022)

Allele C

OR 0.20

p 1.0e-12

N 6,136

Large GWAS

European

vitamin D deficiency

Amin HA et al. “No evidence that vitamin D is able to prevent or affect the severity of COVID-19 in individuals with European ancestry: a Mendelian randomisation study of open data.” Bmj Nutrition, Prevention & Health 4(1):42-48 (2021)

Allele C

OR 0.08

p 1.0e-9

N 175,977

Large GWAS

European

myocardial infarction

Nikpay M et al. “A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.” Nature Genetics 47(10):1121-1130 (2015)

Allele A

OR 1.11

p 3.0e-8

N 166,459

Meta-analysisLarge GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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