rs4977844

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

neuroticism measurement

Luciano M et al. “Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.” Nature Genetics 50(1):6-11 (2018)
Allele G
OR 0.03
p 1.0e-9
N 329,821
Large GWAS
European
Smith DJ et al. “Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci.” Molecular Psychiatry 21(6):749-57 (2016)
Allele G
OR 0.08
p 3.0e-8
N 106,716
Large GWAS
European

neurotic disorder

Cai N et al. “Minimal phenotyping yields genome-wide association signals of low specificity for major depression.” Nature Genetics 52(4):437-447 (2020)
Allele C
OR 0.01
p 4.0e-9
N 274,107
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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