rs530804537
This variant is located in the USP24 gene.
▶GWAS Catalog Trait Associations (7)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (7)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
fish oil supplement exposure measurement, low density lipoprotein cholesterol measurement
Francis M et al. “Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci.” Plos Genetics 17(3):e1009431 (2021)
Allele A
OR —
p 3.0e-31
N 73,832
Large GWAS
European
total lipids in large HDL
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.10
p 2.0e-25
N 450,015
Large GWAS
multi-ancestry
fish oil supplement exposure measurement, total cholesterol measurement
Francis M et al. “Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci.” Plos Genetics 17(3):e1009431 (2021)
Allele A
OR —
p 2.0e-20
N 73,962
Large GWAS
European
free cholesterol in very large HDL measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.07
p 2.0e-15
N 450,015
Large GWAS
multi-ancestry
cholesterol in very large HDL measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.06
p 4.0e-11
N 450,015
Large GWAS
multi-ancestry
concentration of very large HDL particles measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.06
p 6.0e-11
N 450,015
Large GWAS
multi-ancestry
level of Sterol ester (27:1/20:3) in blood serum
Ottensmann L et al. “Genome-wide association analysis of plasma lipidome identifies 495 genetic associations.” Nature Communications 14(1):6934 (2023)
Allele A
OR 0.24
p 4.0e-9
N 7,171
Large GWAS
European
About USP24
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008]
View all USP24 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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