rs537938132

This variant is located in the L3MBTL4 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

type 1 diabetes mellitus

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 2.34
p 4.0e-11
N 627,819
Major Consortium StudyLarge GWAS
multi-ancestry

About L3MBTL4

Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all L3MBTL4 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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