rs539150884
This variant is located in the BRMS1 gene.
▶ClinVar annotation
About BRMS1
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
View all BRMS1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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