rs540459343

This variant is located in the FCGR3B gene.

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ClinVar annotation

Uncertain Significance★☆☆☆

1 submitter

not specified

About FCGR3B

The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]

View all FCGR3B variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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