rs540524
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
glucose measurement
Chen J et al. “The trans-ancestral genomic architecture of glycemic traits.” Nature Genetics 53(6):840-860 (2021)
Allele A
OR —
β 0.039
p 1.0e-49
N 9,343
Large GWAS
South Asian
Lagou V et al. “GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification.” Nature Genetics 55(9):1448-1461 (2023)
Allele A
OR 0.00
p 2.0e-11
N 475,416
Large GWAS
multi-ancestry
HbA1c measurement
Chen J et al. “The trans-ancestral genomic architecture of glycemic traits.” Nature Genetics 53(6):840-860 (2021)
Allele A
OR —
β 0.002
p 4.0e-32
N 146,806
Large GWAS
European
blood glucose amount
Chung RH et al. “Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose.” Diabetologia 64(7):1613-1625 (2021)
Allele G
OR 0.11
p 9.0e-27
N 18,122
Large GWAS
East Asian
DiCorpo D et al. “Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program.” Communications Biology 5(1):756 (2022)
Allele G
OR 0.04
p 1.0e-13
N 26,807
Large GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…