rs542365962
This variant is located in the MCUB gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
atrial fibrillation
Roselli C et al. “Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases.” Nature Genetics 57(3):539-547 (2025)
Allele T
OR 1.30
p 7.0e-9
N 1,650,345
Meta-analysisLarge GWAS
multi-ancestry
About MCUB
Enables calcium channel inhibitor activity. Involved in negative regulation of calcium import into the mitochondrion. Located in cytosol and mitochondrial inner membrane. Part of uniplex complex. [provided by Alliance of Genome Resources, Jul 2025]
View all MCUB variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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