MCUB
mitochondrial calcium uniporter dominant negative subunit beta
Summary
Enables calcium channel inhibitor activity. Involved in negative regulation of calcium import into the mitochondrion. Located in cytosol and mitochondrial inner membrane. Part of uniplex complex. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants6 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs547113723 | 4:110,525,039 | G/A | — | — |
| rs542365962 | 4:110,527,287 | C/T | — | — |
| rs189866430 | 4:110,578,226 | T/A | intron variant | — |
| rs1729166878 | 4:110,580,181 | G/C | — | uncertain significance |
| rs1428355104 | 4:110,581,497 | A/G | — | uncertain significance |
| rs144584495 | 4:110,608,696 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.