rs557787710

This variant is located in the TBC1D21 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

amount of CD276 antigen (human) in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele A

OR 0.90

p 1.0e-24

N 47,745

Large GWAS

European

About TBC1D21

Enables GTPase activator activity and small GTPase binding activity. Predicted to be involved in plasma membrane to endosome transport; sperm axoneme assembly; and sperm mitochondrial sheath assembly. Located in extracellular exosome. [provided by Alliance of Genome Resources, Jul 2025]

View all TBC1D21 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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