rs55880988

This variant is located in the ZFPM1 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

C-reactive protein measurement

Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)

Allele A

OR 0.02

p 1.0e-12

N 436,491

Large GWAS

multi-ancestry

coronary artery disease

Tcheandjieu C et al. “Large-scale genome-wide association study of coronary artery disease in genetically diverse populations.” Nature Medicine 28(8):1679-1692 (2022)

Allele A

OR 0.03

p 5.0e-9

N 1,077,578

Large GWAS

multi-ancestry

About ZFPM1

Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and transcription corepressor activity. Involved in platelet formation; regulation of definitive erythrocyte differentiation; and regulation of gene expression. Part of transcription repressor complex. [provided by Alliance of Genome Resources, Jul 2025]

View all ZFPM1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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