rs55944332

This variant is located in the TEX41 gene.

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

diastolic blood pressure

Plotnikov D et al. “High Blood Pressure and Intraocular Pressure: A Mendelian Randomization Study.” Investigative Ophthalmology & Visual Science 63(6):29 (2022)

Allele A

OR 0.25

p 1.0e-24

N 526,001

Large GWAS

European

Yang ML et al. “Sex-specific genetic architecture of blood pressure.” Nature Medicine 30(3):818-828 (2024)

Allele A

OR 0.02

p 4.0e-18

N 349,328

Large GWAS

multi-ancestry

Wain LV et al. “Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.” Hypertension (dallas, Tex. : 1979) 70(3):e4-e19 (2017)

Allele A

OR 0.27

p 2.0e-19

N 150,134

Large GWAS

multi-ancestry

systolic blood pressure

Koskeridis F et al. “Multi-trait association analysis reveals shared genetic loci between Alzheimer's disease and cardiovascular traits.” Nature Communications 15(1):9827 (2024)

Allele G

OR 0.01

p 1.0e-13

N 1,212,859

Large GWAS

European

wap, kazal, immunoglobulin, kunitz and ntr domain-containing protein 1 measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele G

OR 0.04

p 6.0e-12

N 47,745

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

rs55944332

GWAS Catalog Trait Associations (3)

diastolic blood pressure

systolic blood pressure

wap, kazal, immunoglobulin, kunitz and ntr domain-containing protein 1 measurement

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