rs56236159

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

basigin measurement

Thareja G et al. “Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations.” Human Molecular Genetics 32(6):907-916 (2023)

Allele G

OR 0.22

p 7.0e-12

N 2,935

Large GWAS

Greater Middle Eastern (Middle Eastern, North African or Persian)

diastolic blood pressure

Evangelou E et al. “Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.” Nature Genetics 50(10):1412-1425 (2018)

Allele T

OR 0.13

p 5.0e-9

N 757,601

Large GWAS

European

low density lipoprotein cholesterol measurement

Richardson TG et al. “Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis.” Plos Medicine 17(3):e1003062 (2020)

Allele T

OR 0.02

p 7.0e-9

N 440,546

Large GWAS

European

coronary artery disease

Tcheandjieu C et al. “Large-scale genome-wide association study of coronary artery disease in genetically diverse populations.” Nature Medicine 28(8):1679-1692 (2022)

Allele T

OR 0.03

p 3.0e-8

N 1,077,578

Large GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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