rs571860225

This variant is located in the LRCH1 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Benign Thyroid Gland Neoplasm

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 2.93
p 1.0e-11
N 571,550
Major Consortium StudyLarge GWAS
multi-ancestry

About LRCH1

This gene encodes a protein with a leucine-rich repeat and a calponin homology domain. Polymorphism in this gene may be associated with susceptibililty to knee osteoarthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2010]

View all LRCH1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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