rs573372786

This variant is located in the NPAS2 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Benign Thyroid Gland Neoplasm

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 3.41
p 6.0e-12
N 571,550
Major Consortium StudyLarge GWAS
multi-ancestry

About NPAS2

The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. A similar mouse protein may play a regulatory role in the acquisition of specific types of memory. It also may function as a part of a molecular clock operative in the mammalian forebrain. [provided by RefSeq, Jul 2008]

View all NPAS2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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