rs57348955
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
level of serum globulin type protein
Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.02
p 3.0e-15
N 325,292
Major Consortium StudyLarge GWAS
multi-ancestry
high density lipoprotein cholesterol measurement
Richardson TG et al. “Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis.” Plos Medicine 17(3):e1003062 (2020)
Allele G
OR 0.01
p 7.0e-9
N 403,943
Large GWAS
European
Graves disease
Cooper JD et al. “Seven newly identified loci for autoimmune thyroid disease.” Human Molecular Genetics 21(23):5202-8 (2012)
Allele G
OR 1.20
p 4.0e-8
N 11,649
Large GWAS
European
autoimmune thyroid disease, Hashimoto's thyroiditis, Graves disease
Cooper JD et al. “Seven newly identified loci for autoimmune thyroid disease.” Human Molecular Genetics 21(23):5202-8 (2012)
Allele G
OR 1.19
p 5.0e-8
N 12,097
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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