rs57957974
This is a intron variant variant in the PARP10 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
bipolar I disorder
Stahl EA et al. “Genome-wide association study identifies 30 loci associated with bipolar disorder.” Nature Genetics 51(5):793-803 (2019)
Allele A
OR 1.10
p 2.0e-8
N 46,237
Large GWAS
European
About PARP10
Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors (Yu et al., 2005 [PubMed 15674325]).[supplied by OMIM, Mar 2008]
View all PARP10 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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