rs59677118
This is a intergenic variant variant in the NFIB gene.
▶Research that mentions this SNP (1)
▶A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinksMeta-analysisN=4,915Manav Kapoor et al.(2013)· Human Genetics
A meta-analysis of two genome-wide association studies (COGA and SAGE) identifying genetic variants associated with maximum number of alcoholic drinks consumed in 24 hours (maxdrinks). The study combined 4,915 participants of European descent and found suggestive associations with multiple loci including rs1229984 (ADH1B, p=2.04×10⁻⁸), rs4758317 (LMO1, p=7.2×10⁻⁷), and variants in PLCL1 (p=4.07×10⁻⁶). Approximately 40% of the variance in maxdrinks was explained by genome-wide SNPs.
About NFIB
Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription regulator inhibitor activity. Involved in brain development and regulation of DNA-templated transcription. Located in fibrillar center and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
View all NFIB variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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