rs60154857

This is a intron variant variant in the GAREM1 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

osteoarthritis

Hatzikotoulas K et al. Translational genomics of osteoarthritis in 1,962,069 individuals. Nature 641(8065):1217-1224 (2025)
Allele A
OR 0.97
p 3.0e-9
N 1,962,069
Large GWAS
multi-ancestry

About GAREM1

This gene encodes an adaptor protein which functions in the epidermal growth factor (EGF) receptor-mediated signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

View all GAREM1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…