rs61056117

This is a coding sequence variant variant in the HOTTIP gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

hypertension

Kim YS et al. “Lifestage Sex-Specific Genetic Effects on Metabolic Disorders in an Adult Population in Korea: The Korean Genome and Epidemiology Study.” International Journal of Molecular Sciences 23(19) (2022)

Allele T

OR 0.90

p 1.0e-8

N 50,808

Large GWAS

East Asian

About HOTTIP

This gene produces a long RNA in antisense to the HOXA gene cluster. This transcript may regulate expression of HOXA genes in cis. This gene is upregulated in tumors and is implicated in the promotion of cell proliferation. [provided by RefSeq, Dec 2017]

View all HOTTIP variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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